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Buy Methoxetamine Online, abbreviated as MXE, is a dissociative hallucinogen marketed as a designer drug. It differs from many dissociatives, such as ketamine and phencyclidine (PCP), which were produced as prescription drugs for general anesthetics since they were built for gray market distribution.
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MXE is an arylcyclohexylamine. It primarily acts as an antagonist of NMDA receptors, similar to other arylcyclohexylamines such as ketamine and PCP.
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MXE is said to have an effect similar to ketamine. Due to its structural similarity to 3-HO-PCP, it was often assumed to possess opioid properties, but this assumption is not supported by evidence, which shows negligible affinity by the compound to the μ-opioid receptor. Recreational use of MXE has been associated with high- and/or combined-consumption hospitalizations in the US and UK.Acute reversible cerebellar toxicity has been reported in three hospital admission cases due to MXE overdose, lasting between one and four days after exposure.
MXE was developed in part to prevent the urotoxicity associated with ketamine abuse; it was thought that increased potency of the compound and decreased dose would restrict the accumulation of urotoxic metabolites in the bladder. Like ketamine, MXE was found to cause inflammation of the bladder and fibrosis after high dose, chronic administration in mice (although the dosages used were very large)
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